Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Sickle Cell Anemia with Splenic Sequestration
source: Family Practice Notebook
year: 2018
summary/abstract:Sickle Cell Anemia with Splenic Sequestration:
II. Epidemiology
Most common in ages 1 to 4 years old
III. Pathophysiology
A. Splenic infarction typically occurs by Puberty in patients with Hemoglobin SS
B. However, less severe forms of Sickle Cell Disease can occur in adulthood
IV. Precautions
Rapidly progressive course with significant risk of decompensation secondary to acute Anemia
V. Signs
A. Anemia
B. Abdominal Pain
C. Splenomegaly
1. Acute splenic enlargement (especially in under age 5 years, before auto-infarction)
2. Contrast with Sickle Cell Hemolytic Crisis in which the Spleen will be small or non-palpable
Related Content
-
Strategies to Avoid the FluIt’s cold and flu season and the usual...
-
Virtual reality as complementary pain therapy in hospitalized patients with sickle cell diseaseObjective: Due to incomplete management...
-
Sickle Cell Retinopathyhttps://www.youtube.com/watch?v=tCgAHWvV...
-
The ‘Voice of Lagos’ is silent: Entertainer Tosyn Bucknor dies at 37Nigerians are paying tribute t...
-
GBT expands sickle cell disease pipeline with worldwide licensing agreement for inclacumab for the treatment of vaso...Global Blood Therapeutics, Inc...
-
Safety and early hints of benefit seen in phase 1b trial of PF-04447943Sickle cell disease (SCD) patients were ...
-
Crizanlizumab designated FDA breakthrough therapy for potential in vaso-occlusive crisis preventionCrizanlizumab (SEG101), Novartis‘ inve...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.