Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Microparticles in sickle cell anaemia: promise and pitfalls
source: British Journal of Haematology
year: 2016
authors: Hebbel RP, Key NS
summary/abstract:Blood from patients with sickle cell disease contains microparticles (MP) derived from multiple cell sources, including red cells, platelets, monocytes and endothelial cells. MPs are of great interest because of their disease associations, their status as promising biomarkers, and the intercellular communications they mediate. To illustrate the likelihood of their relevance in sickle cell disease, we discuss the nature of MP, their profiling in sickle disease, some caveats relevant to their detection, their roles in supporting coagulation and the disparate influences they may exert upon the pathobiology of sickle cell disease.
organization: University of Minnesota Medical School, Minneapolis; University of North Carolina at Chapel HillDOI: 10.1111/bjh.14112
read more full text
Related Content
-
Orphan Drugs for Sickle Vaso-occlusion: Dawn of a New Era of Targeted TreatmentWhile an orphan disease in the USA, sick...
-
Computer models provide new understanding of sickle cell diseaseComputer models developed by Brown Unive...
-
Sickle Cell DiseaseSickle cell disease (SCD) is a group of ...
-
Researchers ID key drivers of heart complications in sickle cell anemiaStudy opens path to earlier diagnosis, t...
-
Healthy red blood cells owe their shape to muscle-like structuresRed blood cells are on a wild ride. As t...
-
Small chips, big impact: MSU researcher studies cardiovascular, sickle cell diseaseA Mississippi State University researche...
-
Marina Jerebtsova, PhDDr Marina Jerebtsova is an assistant pro...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.