Google
Trusted Resources: News & Events
Latest announcements and gatherings
Researchers Identify Genetic Predictors of Sickle Cell Anemia-Related Complications
Patients with sickle cell anemia who do not have alpha-thalassemia and the genetic rs1427407 T variant of the BCL11A gene may be at higher risk for hemolysis (rupture of red blood cells) and stroke, according to the results of studies of three independent groups.
These findings were featured in Blood Advances, in the study titled “Associations of α-thalassemia and BCL11A with stroke in Nigerian, United States, and United Kingdom sickle cell anemia cohorts.”
“Our goals were to incorporate individual genetic predictors of sickle cell disease severity into a risk profile to better predict which patients are at higher risk for sickle cell-related complications,” Santosh L. Saraf, MD, lead author of the study, said in a news report. Saraf is an assistant professor of medicine in the department of hematology and oncology at the University of Illinois at Chicago.
+myBinderRelated Content
-
Sickle Cell Disease Management & Complications: Sophie Lanzkron MD of Johns HopkinsStuck on sickle cell disease? We hammer ...
-
Cardinals’ Bruce Arians: WR John Brown carries sickle-cell traitA blood test Thursday revealed that Ariz...
-
Sickle Beta Zero Thalassemia DiseaseSickle Beta Zero Thalassemia (Sickle BA-...
-
Association of Hemoglobin S and C Traits with Kidney Disease in African Americans in the Reasons for Geographic and ...Background: Sickle cell trait (SCT) and ...
-
Healthcare advocates aim to better inform community on sickle cell realitiesOne in 2,400 are born with sickle cell d...
-
MARAC Advisory Statement: Monoclonal Antibodies Against SARS-CoV-2August 26, 2021 – The Sickle Cell Dis...
-
Sickle Cell in Primetime: How A Character Reveal on Shonda Rhimes’ ‘Grey’s Anatomy’ Renewed My HopeIt could be impossible to know when Sick...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.