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L-Glutamine for sickle cell anemia: More questions than answers

key information

source: Blood

year: 2018

authors: Quinn CT

summary/abstract:

In 2017, the Food and Drug Administration approved 2 medications for sickle cell anemia (SCA): hydroxyurea for children and l-glutamine for children and adults. The approval of hydroxyurea was long overdue, but the approval of l-glutamine was a surprise to many. Any effective new treatment for SCA is a welcome advance, but there are few published studies of l-glutamine as a specific treatment for SCA. Accordingly, there are many unanswered questions about its efficacy, safety, and role in current therapy.

organization: Cincinnati Children's Hospital Medical Center, USA

DOI: 10.1182/blood-2018-03-834440

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