Google
Trusted Resources: Community Center
Online groups, photo galleries and blogs
Protein Folding 09: Sickle Cell Disease
Sickle cell disease affects ~70,000 to 100,000 people in the United States, and ~10 million worldwide. The disease was first described by James B. Herrick [Herrick 1910]. The molecular basis was partly elucidated by Linus Pauling and Ibert C. Wells [Pauling 1949], and the exact causal amino acid substitution (E6V) was later identified by V.M. Ingram [Ingram 1956]. This missense variant causes hemoglobin to form long polymers which deform red blood cells into a “sickle” shape.
+myBinderRelated Content
-
National Sickle Cell Advocacy Day 2020 — Sickle Cell Disease Association of America – CANCELEDPlease join the Sickle Cell Disease Asso...
-
Increased prevalence of potential right-to-left shunting in children with sickle cell anaemia and strokeParadoxical' embolization via intracardi...
-
Lisa Pullens, RN, BSN, CPHNLisa received her RN-BSN 33 years ago at...
-
Clint Joiner, MD, PhDDr. Clinton Joiner is a Director of Hema...
-
Realizing Effectiveness Across Continents With Hydroxyurea: Enrollment and Baseline Characteristics of the Multicent...Despite its well-described safety and ef...
-
The Sickle Cell Infusion Center at Johns HopkinsThe Sickle Cell Center for Adults is ded...
-
Adulting is especially difficult for youth with special health care needsThere are approximately 4.3 million adol...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
