Google
Trusted Resources: People & Places
Healthcare providers, researchers, and advocates
Shengdar Q. Tsai, PhD
Researcher Assistant Member
Experimental Hematology Division
St. Jude Children’s Research Hospital
MS 341, Room D3022B
262 Danny Thomas Place
Memphis, Tennessee, United States
Dr. Shengdar Q. Tsai is an assistant member in the Department of Hematology at St. Jude Children’s Research Hospital. He obtained his B.S. in Biochemistry and Chemistry from the University of Michigan, M.S. in Bioinformatics and Ph.D. in Functional Genomics from North Carolina State University. He was a postdoctoral research fellow and instructor at Massachusetts General Hospital and Harvard Medical School. Dr. Tsai has focused on developing methods for high throughput genome editing with TALENs, and defining and improving the genome-wide specificity of CRISPR-Cas nucleases. His long-term research goals are to develop safe and highly specific targeted genome-editing strategies for treating human genetic diseases.
His research interests include:
• Improving genomic methods to define and measure gene editing “off-target” effects
• Protein engineering of CRISPR-Cas nucleases for precise gene correction
• Regulation of DNA damage repair choice between error-prone non-homologous end-joining and precise homology-directed repair
• Genome-scale CRISPR-Cas screening for novel effectors of hematological diseases
• Developing novel strategies for allele-specific editing of genetic mutations that cause sickle cell disease and other hematological disorders
+myBinderRelated Content
-
Teens with Sickle Cell Disease Moving from Pediatric Care to Adult CareMoving from pediatric (children’s) car...
-
Children’s Hospital Oakland Research InstituteDuring our first 50 years, Children’s ...
-
The Affordable Care Act Improves Healthcare Access and Utilization Among Young Adults with Sickle Cell DiseaseIntroduction: The Dependent Coverage Pro...
-
Sickle Cell Disease: Data Saves Lives“One minute I’d be fine, the next mi...
-
SCDAA And MedicAlert Pilot Program ApplicationSCDAA and MedicAlert Pilot Program Impr...
-
Sickle Cell Disease Association of America Michigan Chapter, Inc.The vision of Sickle Cell Disease Associ...
-
Melanie E. Fields, MD, MSCIDr. Fields practices in the Division of ...
