Google
Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Coronavirus Disease Among Persons With Sickle Cell Disease, United States, March 20-May 21, 2020
source: Emerging Infectious Diseases
year: 2020
authors: Julie A Panepinto, Amanda Brandow, Lana Mucalo, Fouza Yusuf, Ashima Singh, Bradley Taylor, Katherine Woods, Amanda B Payne, Georgina Peacock, Laura Schieve
summary/abstract:Sickle cell disease (SCD), an inherited hemoglobinopathy that most commonly affects persons of African ancestry, is estimated to affect 1 in 365 Black persons in the United States . Persons with SCD produce abnormal hemoglobin that causes erythrocytes to become rigid and deform under low oxygen conditions, leading to ischemia–reperfusion injury in the microvasculature with subsequent organ damage and pain. SCD affects nearly every organ system; average life expectancy estimates of affected persons are 43–54 years. Persons with SCD are at increased risk for pulmonary disease and pneumonia.
Previous studies have shown that influenza severity and hospitalization rates are higher among persons with SCD than those without SCD. Thus, persons with SCD could be at higher risk for development of severe disease if infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease (COVID-19). Although empirical data are limited, 16 cases of COVID-19 pneumonia have been reported in persons with SCD , and a study of COVID-19 intensive care unit (ICU) admissions reported 2 (4%) of 48 children had SCD . We describe a large series of COVID-19 cases and associated deaths among persons with SCD in the United States.
organization: Medical College of Wisconsin, USA; Centers for Disease Control and Prevention, USADOI: 10.3201/eid2610.202792
read more
+myBinderRelated Content
-
Social Adjustments & Response to COVID-19 – SCDAAhttps://www.sicklecelldisease.org/wp-con...
-
COVID-19 and Sickle Cell Disease – Biree Andemariam, MDhttps://www.youtube.com/watch?v=mZ_yfFyQ...
-
You Should Get a COVID-19 Vaccine – Koreanhttps://www.youtube.com/watch?v=TCelzDdp...
-
Ron Cook: James Franklin Bracing for ‘Heartache’ of College Football SeasonJames Franklin is Pennsylvania’s highe...
-
COVID-19 Health Alert for People With Sickle Cell Disease and Their Caregivers (Adapted for Sub-Saharan Africa)April 1, 2020 - COVID-19, the coronaviru...
-
COVID-19 Resources | Patient Advocate FoundationCareer Specific Relief Funds USBG Natio...
-
COVID-19 Resources for Non-Profit Leaders and the Community | National Organization for Rare DisordersThe health and safety of those with rare...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.