Or register here
Global Search

Trusted Resources: Evidence & Education

Scientific literature and patient education texts

Back to Evidence & Education / Reference Materials

Management of Proliferative Sickle Cell Retinopathy

key information

source: American Academy of Ophthalmology

year: 2018

authors: Mashal Akhter, Michelle W. Latting, Adrienne W. Scott

summary/abstract:

Proliferative sickle cell retinopathy (PSR) is a vision-threaten-ing complication of sickle cell disease (SCD). Ischemic events in the retina stimulate angiogenesis, resulting in retinal neovascularization.

SCD is caused by a mutation in the HBB gene, which encodes hemoglobin beta. PSR affects up to 40% of hetero¬zygous (HbSC) patients and 20% of homozygous (HbSS) patients. Although most patients remain visually asymptomatic, the incidence of visual loss among patients with HbSS and HbSC affected by PSR has been reported as 31 per 1,000 eyes compared with 1.4 per 1,000 in eyes with nonproliferative disease.

 

read more

Related Content

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close

© 2024 rareLife solutions Inc.

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close