Google
Trusted Resources: Evidence & Education
Scientific literature and patient education texts
Sleep Disturbance in Adults With Sickle Cell Disease: Relationships With Executive and Psychological Functioning
source: Annals of Hematology
year: 2020
authors: Amanda Rhodes, Staci Martin, Pamela Wolters, Yessica Rodriguez, Mary Anne Toledo-Tamula, Kari Struemph, Courtney Fitzhugh, Matt Hsieh, John Tisdale
summary/abstract:Sleep disturbance is common among children with sickle cell disease (SCD) and is related to neurocognitive difficulties. However, research on sleep disturbances and related variables among adults with SCD is extremely limited. The present study examined the relationship between sleep, executive functioning, and emotional functioning among 62 adults (29 females; M age = 32 years, SD = 7.79) with SCD preparing to undergo a stem cell transplant. Participants were administered a neurocognitive evaluation that included objective and subjective measures of executive functioning, and they completed PROMIS self-report measures of anxiety, depression, and pain intensity.
Results showed that about 17% of participants endorsed clinically significant sleep disruptions, while 16.1% and 8% endorsed clinically significant symptoms of anxiety and depression, respectively. Sleep disturbance in these adults was not significantly correlated with objective or subjective measures of executive functioning. Moreover, anxiety, but not depression, was a significant mediator between self-reported sleep difficulties and both objective and subjective measures of executive functioning while controlling for pain intensity. Future research on sleep interventions will be essential for ameliorating the effects of sleep disturbance on executive functioning and anxiety among adults with SCD.
organization: National Cancer Institute, USA; Leidos Biomedical Research, Inc, USA; National Heart, Lung, and Blood Institute, USADOI: 10.1007/s00277-020-04058-7
read more
+myBinderRelated Content
-
How Sickle Cell Affects the Bodyhttps://www.youtube.com/watch?v=RewyXWKJ...
-
Sickle cell warrior documentaryhttps://www.youtube.com/watch?v=ZxC4vtN2...
-
Sickle Cell Trait and Risk of Cognitive Impairment in African Americans: The Reasons for Geographic and Racial Diffe...Background: Sickle cell anemia (SCA) has...
-
Integrated Psychology Support and Comprehensive Cognitive Evaluation Improves Access to Special Education Services f...Background: Children with sickle cell d...
-
Cognitive Function may be Affected in Adults With Sickle Cell Disease, Study SuggestsAdults with sickle cell disease score wo...
-
Living With Sickle Cell Disease: One Person’s Story of Pain and Prejudice and Their Hopes for a Stem Cell TherapyMy name is Marissa Cors, I have sickle c...
-
Brandi Abernethy: Nursing Student, Patient, Single MomWhen she was growing up in St. Petersbur...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.